In most cases, mutations in the core of a protein that replace a smaller nonpolar side chain in the wild-type (e.g., Ala, Val) with a larger nonpolar side chain (e.g., Leu, Ile, Phe, Trp) in the mutant, result in significant destabilization and misfolding of the mutant. What feature of the protein core explains this observation? Why would such a mutation prevent a protein from folding properly? Match the items in the left column to the appropriate blanks in the sentences on the right.
Answers
Explanation:
we are required to fill in the blank spaces in the attachment.
protein side chains are non polar. so the first answer is non polar. These side chains are hydrophobic in nature. so the second blank is hydrophobic. Non polar substances are known to have large number of van der waal forces. the third answer is large and the fourth is vanderwaals contact. the protein core destabilizes only when there is a weakening of vanderwaals contact which brings about mutation.
dear user your answer should look like this:
Interactions of non polar side chains in protein sequence lead to the formation of a tightly packed hydrophobic core. This core is stabilized by a large number of vanderwaals contact. When a mutation occurs, it destabilizes the protein core and weakens vanderwaals contact leading to misfolding
Related Questions
1. Compare and contrast internal fragmentation and external fragmentation. Explain the circumstances where one might be preferred over the other.
Answers
Answer:
Explanation:
Internal fragramentatoin is a form of fragmentation that occur when a process required extra or more space compared to the size of the memory block which is allotted and it is fixed . In order words it indicates that the process uses little space.
External fragmentation is a process that occur when the allotted memory size occur in different variable sizes.
Internal fragmentation is majorly used over external fragmentation when a process required more space than the allotted memory block size.
And external fragmentation is preferred over internal fragmentation when a process is detached or reduced from actual memory.
The body’s internal environment must stay blank
Answers
Which action is designed to increase the safety of a person carrying a microscope from one place to another?
Answers
Answer:
wrapping the electrical cord around the arm of the microscope
Explanation:
How would an asthma attack most like affect oxygen delivery in the body
Answers
Answer:
Oxygen delivery would be decreased due to a decrease in the air intake.
Explanation:
Which of the following is not a current theory regarding global climate change? a. Global warming will stimulate crop growth. b. Even the moderate projections on global warming will cause devastation. c. Higher levels of carbon dioxide in the atmosphere will have no effect. d. Sea levels will rise as a result of global warming.
Please select the best answer from the choices provided A B C D
Answers
Answer:
c
Explanation:just took the test
Flooding has the potential to spread illness and harm infrastructure and ecosystems. Health problems can reduce worker productivity, raise mortality, and have an impact on the availability of food. Thus, option C is correct.
What is impact of global climate change on ecosystem?Droughts that are more frequent and intense, storms, heat waves, rising sea levels, melting glaciers, and warming oceans can all directly harm animals.
Destroy the habitats they rely on for survival, and have a disastrous impact on people's way of life and communities. Dangerous weather events are increasing in frequency or severity as climate change gets worse.
Therefore, Higher levels of carbon dioxide in the atmosphere will have no effect. Food production and human health can be harmed by drought.
Learn more about climate change here:
https://brainly.com/question/12346202
#SPJ6
10. How do the data support your claim above?
Answers
Answer:
The data should support your claim by proving that your correct. If your claim can not be supported by your data then you are incorrect.
Explanation:
Where does the atoms in our food come from?
Answers
Answer:
D. all of these.
Explanation:
How is a polar molecule different from non polar molecule
Answers
Polar molecules differ from nonpolar molecules by having positive and negative ends and stronger intermolecular forces of attraction.
What is this chemical structure?
Answer options
A. Nucleotide
B. Amino Acid
C. Phospholipid
D. Nucleoside
Answers
Answer:
the answer is a, i believe:)
Explanation:
hope this helps love:))
————————-
Which of the following is an aspect of the elastic rebound theory?
a. Energy built up when plates try to get past each other is released when plates break free.
b. Fault zones are often located near major population centers.
C. Earthquakes occurring along subduction zones cause tsunamis.
d. None of the above are aspects of the elastic rebound theory.
Answers
Answer:
Energy built up when plates try to get past each other is released when plates break free.
Explanation:
Answer:
A
Explanation:
Edge 2020
How can some thing as massive as a Pacific plate move
Answers
Answer:
convection currents
Explanation:
convection currents in the Earths mantle allow the tectonic plates to slide and grind up against each other.
Please help I’ll cashapp and mark brainless
Answers
Answer:
d.
Explanation:
Making observations. :)
Answer:
b. testing hypothesis
Explanation:
what do you test in history and art, nothing
A potassium ion (K+) would most likely bond with
Answers
Please let me know if this helped :)
What are the radioactive elements?
Answers
Answer:radium ,radon ,polonium
Explanation:hope this helps []~(￣▽￣)~*
Shane chose a nonfiction book about styles of dress during the 1920s. It contained factual stories, information, and pictures of people and wardrobes during the time period. What was most likely Shane’s purpose for choosing the text?
A.to read a funny story
B.to discover something new
C.to find out how to make something
D.to find out what people think about the past
Answers
Answer:
I think it’s A
Explanation:
If it’s wrong I’m sorry
Answer:its A 100%
Explanation:
A.to read a funny story
B.to discover something new
C.to find out how to make something
D.to find out what people think about the past
Which statement is FALSE? First exclude the four that are correct. While performing photosynthesis during the day, the chloroplasts of a green leaf produce Which statement is FALSE? First exclude the four that are correct. While performing photosynthesis during the day, the chloroplasts of a green leaf produce ATP to be used in the Calvin cycle. ATP as an energy source for the roots of the plant. sugars for the green leaf’s cellular respiration at night. sugars as an energy source for the roots of the plant. sugars to fuel the growth of the plant.
Answers
Answer:ATP as an energy source for the roots of the plant.
Explanation:
Photosynthesis is the process by which plants manufacture their own food. It involves the combination of water and carbon dioxide in the presence of sunlight. Sugars are produced in the process.
The ATP molecules produced during photosynthesis are not transported to plant root cells. Rather, metabolic activities within the plant root cells produces the energy molecules required by the plant roots.
Quickly research ribosomes; what macromolecules make up ribiosomes (pick 2)?
Answers
Answer:
Ribosomes are made up of macromolecule "nucleic acids " especially RNA ( ribonucleic acid)
What is the length of the y component of the vector shown below?
a. 5
b. 4
c. 2
d. 0
Answers
Answer:
5
Explanation:
What is the length of the y component of the vector shown below?
a. 5
b. 4
c. 2
d. 0
Answer:
c. 2
Explanation:
count 2 down on the y-axis
"Histology Lab Tissues are groups of cells with similar shape and function. The purpose of this lab is to give you experience looking at and identifying tissue slides taken from areas all over the body. Epithelium 1. What is the primary purpose of all epithelial tissue? 2. Besides skin, give two examples of different body "surfaces" that are exposed to the outside environment and would need a lining of epithelium. 3. Label the following as squamous, cuboidal, or columnar."
Answers
Answer:
1. The primary purpose of all epithelial tissue is to cover the different body surfaces, this includes cavities that are not in contact with the exterior and parts of the body that are in contact with the exterior.
2. Tongue and esophagus.
3. The images with the types of epithelium are attached.
Explanation:
The main purpose of epithelial tissue is to cover all the surfaces of our body. These are the cavities, and the parts that are in contact with the exterior. They create barriers that protect the body, secrete, absorb substances, allow the passage of specific elements, and stop the entrance of others. The functions vary according to where the tissue is in the body.
The tongue, as it is in contact with the exterior and with the food that enters our mouth, it has a stratified squamous epithelium. The thickness of this epithelium protects it against the different things that can damage or enter through it.
The esophagus has a nonkeratinized stratified squamous epithelium that protects the esophagus from the damage, that food or antigens may cause.
Squamous epitheliums have cells with a not specific shape that has their nucleus in the center.
Cuboidal epithelial have lined cells with a cuboidal shape.
Columnar epithelial have lined cells with a rectangular shape, and their nucleus is near the basal region.
Which of the following is not a cycle of matter?
O Nitrogen Cycle
O Energy Cycle
O Water Cycle
O Carbon Cycle
Answers
Nutrient cycle is also known as the cycle of matter. Nitrogen, water and carbon all three are cycle of matter but energy cycle is not. Thus, correct option is B.
What is Nutrient Cycle?
Cycle of matter are also known as Biogeochemical cycles. These cycle include both biotic and abiotic factors. Cycle of matter are described into five types based on matter: a. water cycle, b. nitrogen cycle, c. phosphorus cycle, d. sulfur cycle, e. carbon cycle.
Matter constantly moves in the cycle involving change in the state. The matter cycles are essential as they recycle important nutrients required for the survival of living organisms.
In contrast to this, energy flows in the atmosphere. It is the interaction between the energy sources within Earth. The interaction between energy sources and Earth's atmosphere is very significant and a small change could lead to significant change in climate behavior of an area.
Therefore, the correct option is B. Energy cycle is not a cycle of matter.
Learn more about nutrient cycle here:
https://brainly.com/question/13046612
#SPJ2
At one time, people believed that living things could develop from nonliving matter, an idea known as spontaneous generation. Which of these ideas has replaced the idea of spontaneous generation?
Group of answer choices
A)All living things are composed of cells.
B)All matter is made up of atoms.
C) All cells come from pre-existing cells.
D)Cells are the basic units of structure and function in living things.
Answers
Answer:
D. Cells are the basic units of structure and function in living things.
Explanation:
im not sure of my answer
explain the resistence ......?? follow me gyus
Answers
Explanation:
is there multiple choice?
monomers are called carbohydrates are linked together to form fat molecules, or ______
Answers
Answer:
polymer
Explanation:
Hope that helps!
Polysaccharides are 1000s of monosaccharides joined together.These carbohydrates store energy and help build structural compounds. For example, plants use cellulose to build up their cell walls so they can stay rigid and grow towards the sunlight. Plants can store glucose energy in the form of starch in roots, fruits, and seeds. On the other hand, animals store glucose energy in the form of glycogen. When we don't have enough food to eat to replenish glucose in our cells, glycogen will release glucose energy as backup.
True or False??
Answers
Answer:
True
Explanation:
As rightly stated in this question, Glycogen is a carbohydrate which animalsa store glucose energy as. When we eat food, all parts is not converted to glucose, some is converted to glycogen, which is then stored in the liver and muscle tissues.
This stored glycogen, which is a polymer of glucose is broken down to glucose for use during a low supply of glucose to the cells. Hence, it is TRUE that when we don't have enough food to eat to replenish glucose in our cells, glycogen will release glucose energy as backup.
The graph shows the change in temperature of a sample of water in a closed system as thermal
energy is added over time.
150°C -
100°C
Temperature (°C)
50°C
0°C-
-50°C
10
50
60
20 30 40
Time (min)
What happens to the temperature of the water when it begins to melt?
Answers
Answer:
When you heat ice, its temperature rises, but as soon as the ice starts to melt, the temperature stays constant until all the ice has melted.
According to the graph, the temperature of the water continues to increase during the change of state. Thus, the correct option for this question is A.
What will happen if the ice melts?When the ice melts, the level of seawater would tend to be increased. This is because solid ice has tended to change its state to liquid. And now liquid may increase the density of the seawater which ultimately rises its level.
It is noted that when the temperature reaches that 0°C. For some instances of time, it will remain the same, but as time passes it tends to increase. The same principle is seen when the temperature reaches 100°C. So, it can not be said that the temperature remains at 0°C or 100°C until the changes in state.
Therefore, the temperature of the water continues to increase during the change of state. Thus, the correct option for this question is A.
To learn more about Temperature and change of state, refer to the link:
https://brainly.com/question/27988898
#SPJ2
Which example illustrates public scientific communication?
A. A scientist collaborates with other scientists to plan an experiment.
B.A scientist sends a preview copy of a journal article to some colleagues.
C. A federal government agency holds a press conference to describe the response to and the dangers of a new virus epidemic.
D. A federal government agency publishes an article in a professional scientific journal detailing technical details of a new virus.
Answers
ANSWER :
c.A federal goverment agency hold apress conference to and the dangers of a new virus epidemic
What is the volume of a block charger (must be in centimeters)
Answers
Answer:[tex]\lim_{n \to \infty} a_n \neq \sqrt{x} x^{2} \\[/tex]
Explanation:
The sodium-potassium pump is a specialized type of transport protein found in your cell membranes. The pump's
job is to move potassium ions into the cell in
the direction of low to high concentration. In order for this to happen, the cell uses energy
to operate the pump. This is an important step in the function of our
nerve cells. What type of transport does the sodium-potassium pump use?
A. Diffusion
B. Active Transport,
C. osmosis
D. Passive Transport
Answers
Answer:
Active Transport
Explanation:
Active Transport requires energy input
Need help noooooo caaappppp
Answers
Answer:
ok what is your questions and technical discussion and answers from the medulla up to the whole length of the vertebral column any less than the average salary is a great day out, but it would like us know when to go through it all in the category, the first one of our customers with other types and the basic principles, but it would like us know when to go through it all within
Explanation:
easy reach of the following are the best way to get the best way to get the best way to get the best way to get the best way to get the best way to get the best way to get the most popular of my friends are the details
What type of reaction is the following? HELPPPPPP
ASAPPPP
Answers
Answer:
it's synthesis........
two different atoms/molecules form a different compound.
Answer:
Hey!
You were correct! The answer IS Synthesis!
Explanation:
Synthesis : is the process by which one or more chemical reactions are performed with the aim of creating a new compound substance...
In this case Potassium (K) and Chlorine ([tex]Cl_{2}[/tex]) synthesize to create Potassium Chloride!
I HOPE THIS HELPED YOU!