how does SCAAR relate to modern times

Answers

Answer 1

Answer:

Explanation:ll scars tell a story. A childhood fall, an adult fight, an accident, an assault—all will leave their mark. In modern times, the elective scar of a surgical incision has gone from the large heroic scars (the bigger the better) of general surgery, to the carefully planned, minimally invasive incisions of modern times. Once the sign of a great surgeon, the prestigious elective scar is now the nearly invisible scar. The contributions of war-related medical advances represent an important chapter in medical history. Survival from the complex blast/burn/bullet injuries of modern weapons is nearly assured and provides new challenges for recovery. Thus, the history of scars, from ancient wounds to the horrendous scars that signify survival from grievous injury, tells the story of not only human resilience, but of medical miracles.

Scars result from healing without regeneration through the deposition of collagen and fibrous connective tissue. Why the salamander can regenerate a leg and other tissue, but a human cannot, is an evolutionary conundrum. A common laboratory regeneration model is the Mexican axolotl (Fig. 1-1). This endangered species regenerates entire limbs as well as nervous tissue. Mammals are known for some specific regenerative capacities, like antlers in the deer family, which are shed and regrown annually. Humans may be able to regenerate the endometrium, liver, and kidney, but only minimal segments of fingers or toes. In general, humans heal after injury by the formation of scar tissue as a means of bridging the defect, whether it involves only skin or larger chunks of skin muscle and bone.

What is the evolutionary advantage of healing by scar versus regeneration? Energy requirements for wound healing in humans are well documented. For a simple femur fracture, the bedridden patient who normally requires 2,500 calories per day may require up to 6,000 calories per day.1 Burns, in particular, result in high caloric requirements during recovery and are significant scar-forming injuries.2 Burns involving less than 20% of the total body surface and wartime amputations were frequently fatal until nearly the end of the 19th century, and only slightly larger burns until well after 1950. The relative efficiency in time and energy requirements for scar healing compared to regeneration after major injury is likely an evolutionary advantage for the species, if not for the modern individual.

As the complex biology of wound healing becomes increasingly understood, greater insights into the modulation of healing and vertebrate regeneration are emerging. Genetic manipulation in one mouse species has even restored regenerative capacity. The Lin28a gene, silenced in maturing vertebrates, restores regenerative ability when turned on in mouse infancy, but not in maturity.3 Another species, the African spiny mouse, can heal full-thickness skin injuries without scarring. Current intensive research on the use of stem cells for regeneration is widespread, as are clinical practices promoting their use, despite limited documentation in controlled clinical trials. The identification of the Lin28a and b genes and their role in stem cell regeneration is also being rapidly elucidated.4 These concepts offer the promise of future transformative approaches to healing human tissues.

Scars are destined to become part of medical lore if the full potential of current research on genetic manipulation, embryonic healing, and stem cell applications is achieved. The management of scars to date has depended on the prevention of injury, the optimization of wound healing, and the direct treatment of scars after they have formed. This chapter will explore the progress in scar care through history, as well as the meaning scars have had in medicine, law, and literature. So many different individuals have contributed to our knowledge of wounds, their management, and the diagnosis and treatment of scars that not all of them can be introduced in this chapter. Table 1-1 provides an outline of the more important events in the years preceding the modern era of wound care and scar management. I have chosen not to focus on events of this modern era. Rather, I have offered my own view of some of the key people and events prior to the last 60 years. More recent advances are the province of other authors in their respective chapters.


Related Questions

What natural disasters contributed to the fall of the Han?

Answers

The collapse of the Han Dynasty

The Eastern Han emperors faced a variety of challenges, including natural disasters outside of their control, such as cattle plagues, locusts, droughts, floods, and earthquakes.

Answer:

such as cattle plagues, locusts, droughts, floods, and earthquakes. plz count as brinliest

Explanation:

Describe the goods sold and the cultural events displayed in the Indian Curio Rooms.

Answers

Answer:

displayed items liken handwoven baskets, weavings, ornaments, books and household items.

Explanation:

The Indian Curio Rooms showcased and sold different varieties of goods from the SouthWest as well as from Mexico and other places. It displayed items liken handwoven baskets, weavings, ornaments, books and household items which could also be bought by the visitors.

The Curio Rooms also incorporated cultural displays like craft making, story and folklore telling and showcased Indian dances to enhance more visitors to visit and learn about the history of the natives.

a flower is ready to become a fruit. where would the instructions be found

Answers

Answer is A. Nucleus.

Flower is the reproductive organ of a flowering plant that contains male reproductive organ ( stamen) and female reproductive organ (carpel). Anther of the stamen produces male gamete and within the ovary of the carpel produced female gamete. After fertilization male gamete and female gamete fuses to form zygote.  Zygote is a single cell whose nucleus has chromosomes, where all the genetic information regarding development of fruit and seed are stored.    

Answer:

nucleous srry for spelling wrong if i did

Explanation:

Which of the following statements is false?
a.
The town of Victoria was named after the first state representative from Texas.
b.
The town of Victoria was a Mexican colony headquarter.
c.
Refugio and San Patricio were both Irish colony headquarters.
d.
Saltillo was the capital of Coahuila y Texas.


Please select the best answer from the choices provided

A
B
C
D

Answers

C Is the incorrect answer

Answer: B is your answer

Explanation: I took the quiz

What item or export is popular in Virginia

Answers

Answer:soybeans

Explanation:

Answer:

Explanation:

Virginia's top export, dollarwise, is soybeans. Soy oil is fueling growth in the Medeiterannean and North Africa, a new focus for the state, and one of several targets McAuliffe has on his radar for 2015 trade missions. In Asia, it's lumber, peanuts, "containerized soy" and animal feed fueling the growth.

(PLEASE RESPOND QUICK)How did the French have an
advantage over the Indians?

Answers

Answer:

The war provided the french enormous territorial gains in North America, but disputes over subsequent frontier policy and paying the war's expenses led to colonial discontent which led the the american revolution.

Explanation:

Why did the League of Nations lack effectiveness?

Answers

Answer:

Because of the lack of US involvement in the world matters, the rising tensions in the world and because of the inaction and lack of willingness to deal with the problems

The League of Nations were formed shortly after the end of WWI and the United States went back to the policy of isolationism and the allies adopted a policy of appeasement and neutrality which further gave the impression that it was allowed to do whatever they wanted.

What is the purpose of the Preamble?​

Answers

Answer:

The purpose of the preamble is to state what the founding fathers' purpose was, and what they wanted to achieve from writing the Constitution.

Hope this is helpful!

Very beginning of constitution

HHHHHEEEEELLLLLPPPPP!!!!!!
According to the catholic church what was the purpose of the Crusades?
A. To ensure the spread of religious equity
B. To rescue the Holy Land and return its power to the Christians
C. To assist the Islamic army in the Holy Land
D. To assist the king in protecting his lands

Answers

Answer:

B

Explanation:

To rescue the holy lands from the expansion of muslim states.

Please help now
What territory was gained before the Spanish-American War?
Cuba
Guam
Hawaii
Puerto Rico

Answers

Explanation:

Cuba, Guam, Puerto Rico and the Philippines

During criminal cases, what is guaranteed by the Constitution?

media coverage
trial by jury
an experienced lawyer
a panel of justices

Answers

Answer:

Trial by jury

Explanation:

This is something huge in our constitution and you are guaranteed to have jury.

Trial by jury is guaranteed by the constitution during criminal cases.

What is trial by jury?

A jury refers to a group of people who are law abiding in a community; who have been assigned to pronounce an impartial decision on a legal issue.

Here, it is the duty of the jury to make a decision on any criminal case, however, the final application of the decision is done by the judge. It is therefore different from a bench trial where a judge or panel of judges makes all decisions.

Hence, trial by jury is guaranteed by the constitution during criminal cases.

Learn more about trial by jury here: https://brainly.com/question/20662508

PLEASE HELP AND HURRY!!!!!

When he came to power in 1985, Soviet leader Mikhail Gorbachev

A. was seen as unlikable and opposed to change.
B. refused to meet with President Reagan.
C. hoped to improve relations with the West.
D. threatened aggressive military action against the United States.

Answers

Answer:

The foreign policy of the Ronald Reagan administration was the foreign policy of the United States from 1981 to 1989. The main goal was winning the Cold War and the rollback of Communism—which was achieved in the Revolutions of 1989 in Eastern Europe during 1989 and in the Dissolution of the Soviet Union in 1991. Historians debate whom to credit, and how much. They agree that victory in the Cold War made the U.S. the world's only superpower, one with good relations with former Communist regimes in Russia and Eastern Europe

When he came to power in 1985, Soviet leader Mikhail Gorbachev:  hoped to improve relations with the West.  The correct option is C.

When Mikhail Gorbachev became General Secretary he took several reforms that aimed at addressing the Soviet Union's problems. Gorbachev aspired to improve relations with the West as part of these changes.

Through political transparency, Mikhail Gorbachev's programmes attempted to reinvigorate the Soviet economy and minimise disputes between the East and the West. Gorbachev attempted to normalise relations with the West in order to alleviate Cold War tensions.

Thus, the ideal selection is option C.

Learn more about Mikhail Gorbachev here:

https://brainly.com/question/27672234

#SPJ4

PLEASE HELP!!!
Chief Justice John Marshall is responsible for __________.
A.
taxing the states
B.
overturning the Treaty of Paris
C.
establishing the role of the Supreme Court in judicial review
D.
writing the supremacy clause

Answers

Answer:

c. on edge

Explanation: i took the test

establishing the role of supremecy

Answer:

the answer is C. establishing the role of supreme court in a judical review

Explanation:

hope this helps

Why did it take so long for the Renaissance to take root in England?

Answers

Answer:

Explanation:

Peasants working on feudal lands in England in 1310. ... Feudalism was much more present in European society outside of Italy which caused the ideas of the Renaissance to spread slowly. This was because Feudal society was not as open to new ideas as the city-states that existed in Italy at the time. I think.

Which battle do you think was most important in establishing the eventual victory of the colonies over Britain?
answer in full sentences (100 points!!!)

Answers

When the French and Indian War finally ended in 1763, no British subject on either side of the Atlantic could have foreseen the coming conflicts between the parent country and its North American colonies. Even so, the seeds of these conflicts were planted during, and as a result of, this war. Keep in mind that the French and Indian War (known in Europe as the Seven Years' War) was a global conflict. Even though Great Britian defeated France and its allies, the victory came at great cost. In January 1763, Great Britain's national debt was more than 122 million pounds [the British monetary unit], an enormous sum for the time. Interest on the debt was more than 4.4 million pounds a year. Figuring out how to pay the interest alone absorbed the attention of the King and his ministers.

The war was fought primarily along the frontiers separating New France from the British colonies from Virginia to Nova Scotia. The Ohio Country (sometimes called the Ohio Territory or Ohio Valley by the French) was the name used in the 18th century for the regions of North America west of the Appalachian Mountains and in the region of the upper Ohio River south of Lake Erie. The territory encompassed roughly the present-day states of Ohio, eastern Indiana, western Pennsylvania, and northwestern West Virginia. The issue of settlement in the region is considered to have been a primary cause of the French and Indian War and a later contributing factor to the American Revolutionary War.

Please help I’ll give brainiest!

Answers

Answer:

offer more points and I'll answer all 12...5points not worth it tbh

1. massachusetts
2. new hampshire
3. connecticut
4. rhode island
5. new york
6. pennsylvania
7. new jersey
8. maryland
9. delaware
10. virginia
11. north carolina
12.south carolina
13. georgia

The role of the General
Assembly is to make laws
for this branch Of
State government

which branch is that?
legislative, judicial, or executive

Answers

the legislative branch

Which of the following was a major cause of social unrest in Russia in 1900?

Question 1 options:

There was a wide egap economically between the nobility and the peasants.


Marxist revolutionaries were trying to overthrow Tsar Nicholas II.


Communists took ownership of land, mines, and factories.


The Russian monarchy (the tsars) abolished serfdom decades earlier.

Answers

i believe it’s c but i’m not sure if it’s correct

Hi there! Your answer would be A) There was a wide gap between the nobility and the peasants. I've taken the test myself and that was the correct answer. Hope that helps and have a great day :)

Please read the quote and tell me what plan is it!

Answers

Answer:

virgnia plan

Explanation:

__________ is defined as a gathering of people, often for a specific purpose.

Answers

Answer:

meeting

Explanation:

i guess..........

Answer:

seminar I thought because people gather there for specific purpose

Why did the delegates at the Constitutional Convention of 1787 agree to the Three-Fifths Compromise?

Answers

Answer: it resolved the question of representation in congress

Explanation: just took the test

How did new scientific discoveries in the sixteenth and seventeenth century improve people's lives and lead to the growth of capitalism?​

Answers

Answer: the discovery of the subamirine in 16th century helped people explore the ocean this helped captilism by getting funding

Explanation:

PLEASE HELP MY QUICK( look at picture)

Answers

Answer:

They improved because all of the schools had to help all together for the Georgia

Explanation:

how did the enlightenment influence the French revolution?​

Answers

Answer:

Impact. The ideas of the Enlightenment played a major role in inspiring the French Revolution, which began in 1789 and emphasized the rights of common men as opposed to the exclusive rights of the elites. As such, they laid the foundation for modern, rational, democratic societies.

Explanation:

Which country's independence movement was Jomo Kenyatta connected to? (4 points)


India


Libya


Jamaica


Kenya

Answers

Kenya because Jomo Kenyatta was Kenya's anti-colonial and activist leader.

Reconstruction tried to solve the problems by...

Answers

Answer:

After the Civil War, people of the North and the South were united back into one full country. As a losss to the north, the south were given reparations to rebuild their civilization.

!!!!!!!!!!! the earth is flat and it looks round becuase of the dome!!!!!!!!!!!!!!

Answers

i think that the earth is round

HELPPP !!!! Explain how the ideas of the government of the United States were shaped by events in England
history.

Answers

The colonist who came from England wanted freedom from religion, and they wanted to live in a more freer country than England. So they created their own colonies (owned by England but since they were so far the colonies had governors).

What did the nobles hope to accomplish by having King John sign the Magna Carta?


PLEASE HELP ITS URGENT!!!!!!!​

Answers

Answer:

The Magna Carta protected people from heavy taxes and unjust imprisonment. This idea of protecting the rights of people lay the foundation for democratic rule in England and America.

Explanation:

Answer:to prevent the king from having the power to abuse rights and inflict injustices

According to the text, why is Temple Mount important to Muslims? Check all that apply.
It is the site where Prophet Mohammad received his winged horse, Buraq.
It is the holiest place in Islam.
It is the location where Prophet Mohammad began his ascent to heaven.
It is one of the oldest surviving Muslim monuments in the world.

Answers

Answer:

It is the location where Prophet Mohammed began his ascent to heaven .

It is one of the oldest surviving Muslim monuments in the world.

Explanation:

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